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Article

The molecular chaperone Hsp90 plays a role in the assembly and maintenance of the 26S proteasome.

The EMBO journal - 15 Jul 2003

Imai Jun, Maruya Mikako, Yashiroda Hideki, Yahara Ichiro, Tanaka Keiji

Abstract excerpt

Hsp90 has a diverse array of cellular roles including protein folding, stress response and signal transduction. Herein we report a novel function for Hsp90 in the ATP-dependent assembly of the 26S proteasome. Functional loss of Hsp90 using a temperature-sensitive mutant in yeast caused dissociati...

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Identifiers

PMID: 12853471
DOI: 10.1093/emboj/cdg349
PMCID: PMC165619

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-12853471-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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