Article
Structure and function of the ftsH gene in Escherichia coli.
Research in microbiology - 1 Jan 2000
Ogura T, Tomoyasu T, Yuki T, Morimura S, Begg K J, Donachie W D, Mori H, Niki H, Hiraga S
Abstract excerpt
The ftsH mutant Y16 shows thermosensitive filamentation with reduced amounts of penicillin-binding protein 3 (PBP3) (Ferreira et al., 1987). Genetic analysis, however, showed that the lethality of the ftsH mutation was not due to a lack of PBP3 activity alone. The ftsH gene was cloned and sequenced and the FtsH protein was deduced to be a membrane protein of 70.7 kDa which has an ATP-binding domain. Highly...
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