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Article

Roles of multimerization and membrane association in the proteolytic functions of FtsH (HflB).

The EMBO journal - 1 Aug 2000

Akiyama Y, Ito K

Abstract excerpt

FtsH (HflB) is an Escherichia coli ATP-dependent protease that degrades some integral membrane and cytoplasmic proteins. While anchored to the cytoplasmic membrane by the two transmembrane (TM) segments near the N-terminus, it has a large cytoplasmic domain. The N-terminal region also has a role in homo-oligomerization of this protein. To study the significance of the membrane integration and oligomer formation,...

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Identifiers

PMID: 10921871
DOI: 10.1093/emboj/19.15.3888
PMCID: PMC306588

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

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Roles of multimerization and membrane association in the proteolytic functions of FtsH (HflB).PMID 10921871Read ↗

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