Article
Genetic analyses of integrin function in mice.
Current opinion in cell biology - 1 Oct 1996
Fässler R, Georges-Labouesse E, Hirsch E
Abstract excerpt
Recent mutations of most integrin genes in the mouse have provided new exciting insights into the role of these integrins in cell-extracellular matrix interactions during development. The embryonic lethal phenotypes obtained by ablating integrins which are predominantly expressed in the mesenchyme confirmed the essential function of those integrins in morphogenesis. In contrast, null alleles for several...
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