Article
APOE-epsilon 4 in patients with Alzheimer disease and vascular dementia.
Alzheimer disease and associated disorders - 1 Jan 1996
Treves T A, Bornstein N M, Chapman J, Klimovitzki S, Verchovsky R, Asherov A, Veshchev I O, Korczyn A D
Abstract excerpt
The apolipoprotein E (APOE) epsilon 4 allele has been consistently found to be frequent in patients with progressive degenerative dementia of the Alzheimer type (DAT). Vascular dementia (VD) may occur as strokes superimposed on presymptomatic DAT, in which case APOE-epsilon 4 frequency should also be increased in VD. We have examined the distribution of APOE-epsilon 4 in patients with DAT (n = 176) or VD (n = 74)...
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