Article
Enhanced LTP in mice deficient in the AMPA receptor GluR2.
Neuron - 1 Nov 1996
Jia Z, Agopyan N, Miu P, Xiong Z, Henderson J, Gerlai R, Taverna F A, Velumian A, MacDonald J, Carlen P, Abramow-Newerly W, Roder J
Abstract excerpt
AMPA receptors (AMPARs) are not thought to be involved in the induction of long-term potentiation (LTP), but may be involved in its expression via second messenger pathways. However, one subunit of the AMPARs, GluR2, is also known to control Ca2+ influx. To test whether GluR2 plays any role in th...
Topics
- Animals
- Behavior, Animal
- Blotting, Western
- Calcium
- Cell Membrane Permeability
- Electrophysiology
- Hippocampus
- Long-Term Potentiation
- Membrane Potentials
- Mice
- Mice, Knockout
- Mutation
