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Article

Enhanced LTP in mice deficient in the AMPA receptor GluR2.

Neuron - 1 Nov 1996

Jia Z, Agopyan N, Miu P, Xiong Z, Henderson J, Gerlai R, Taverna F A, Velumian A, MacDonald J, Carlen P, Abramow-Newerly W, Roder J

Abstract excerpt

AMPA receptors (AMPARs) are not thought to be involved in the induction of long-term potentiation (LTP), but may be involved in its expression via second messenger pathways. However, one subunit of the AMPARs, GluR2, is also known to control Ca2+ influx. To test whether GluR2 plays any role in the induction of LTP, we generated mice that lacked this subunit. In GluR2 mutants, LTP in the CA1 region of hippocampal...

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Identifiers

PMID: 8938126
DOI: 10.1016/s0896-6273(00)80225-1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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