Article
Uroporphyria induced by 5-aminolaevulinic acid alone in Ahrd SWR mice.
Biochemical pharmacology - 8 Nov 1996
Constantin D, Francis J E, Akhtar R A, Clothier B, Smith A G
Abstract excerpt
In mice, depression of hepatic uroporphyrinogen decarboxylase (UROD) leading to porphyrin accumulation (uroporphyria) occurs with chlorinated ligands of the aryl hydrocarbon (AH) receptor especially after iron overload. However, in the absence of chlorinated ligands, iron itself will eventually c...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
