Article
Longitudinal study of a mouse model of familial porphyria cutanea tarda.
Cellular and molecular biology (Noisy-le-Grand, France) - 1 Jul 2009
Arch D D, Bergeron M, Hathaway L, Kushner J P, Phillips J D, Franklin M R
Abstract excerpt
Most rodent models of porphyria cutanea tarda (PCT) share in common the administration of iron and agents that induce transcription of cytochrome P450s. Dissection of changes related to porphyrin accumulation required generation of a genetic model free from exogenous precipitants. Mice heterozygo...
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