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Article

A microplate assay for K-ras genotyping.

European journal of clinical chemistry and clinical biochemistry : journal of the Forum of European Clinical Chemistry Societies - 1 Oct 1996

Berndt C, Wolf G, Schröder G, Bebenroth M, Oehlschlegel K, Hillebrand T, Zanow J

Abstract excerpt

The paper presents a microplate hybridisation assay for the detection of codon 12 mutations of the K-ras protooncogene. Single-stranded target DNA, obtained from amplifying sample DNA with 5'-biotin and 5'-digoxigenin-labelled primers and subsequent strand separation, is hybridised with solid pha...

Topics

Codon
DNA Mutational Analysis
Genes, ras
Genotype
Humans
Polymerase Chain Reaction
Sensitivity and Specificity
Tumor Cells, Cultured

Source

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Identifiers

PMID: 8933108

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-8933108-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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