Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

KRAS mutation screening by chip-based DNA hybridization--a further step towards personalized oncology.

The Analyst - 21 Apr 2015

Steinbach Christine, Steinbrücker Carolin, Pollok Sibyll, Walther Katharina, Clement Joachim H, Chen Yuan, Petersen Iver, Cialla-May Dana, Weber Karina, Popp Jürgen

Abstract excerpt

The use of predictive biomarkers can help to improve therapeutic options for the individual cancer patient. For the treatment of colon cancer patients with anti-EGFR-based drugs, the KRAS mutation status has to be determined to pre-select responders that will benefit from this medication. Amongst others, array-based tests have been established for profiling of the KRAS mutation status. Within this article we...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cell Line, Tumor
Share to Codon

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Microfluidic Analytical Techniques

Share to Neoplasms

Share to Nucleic Acid Hybridization

Share to Precision Medicine

Share to Proto-Oncogene Proteins p21(ras)

Share to Silver

Source

Identifiers

PMID: 25706807
DOI: 10.1039/c4an02086c

Genes

KRAS
EGFR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

KRAS mutation screening by chip-based DNA hybridization--a further step towards personalized oncology.PMID 25706807Read ↗

An oligonucleotide-tagged microarray for routine diagnostics of colon cancer by genotyping KRAS mutations.Semantic proximity Read ↗

Nucleotide-selective amplification and array-based detection for identifying multiple somatic mutations.Semantic proximity Read ↗

KRAS mutation detection in colorectal cancer by a commercially available gene chip array compares well with Sanger sequencing.Semantic proximity Read ↗

Genotyping of KRAS Mutational Status by the In-Check Lab-on-Chip Platform.Semantic proximity Read ↗

Hybridization-Induced Aggregation Technology for Practical Clinical Testing: KRAS Mutation Detection in Lung and Colorectal Tumors.Semantic proximity Read ↗

DNA microarray-based solid-phase PCR on copoly (DMA-NAS-MAPS) silicon coated slides: An example of relevant clinical application.Semantic proximity Read ↗

A new microarray substrate for ultra-sensitive genotyping of KRAS and BRAF gene variants in colorectal cancer.Semantic proximity Read ↗

Rapid KRAS Mutation Detection via Hybridization-Induced Aggregation of Microbeads.Semantic proximity Read ↗

Developing a Low-Cost, Simple-to-Use Electrochemical Sensor for the Detection of Circulating Tumour DNA in Human Fluids.Semantic proximity Read ↗

Kras gene codon 12 mutation detection enabled by gold nanoparticles conducted in a nanobioarray chip.Semantic proximity Read ↗

Detection of single nucleotide polymorphisms by minisequencing on a polypyrrole DNA chip designed for medical diagnosis.Semantic proximity Read ↗

Miniaturized Real-Time PCR on a Q3 System for Rapid KRAS Genotyping.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.