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Article

Diagnostic biochip array for fast and sensitive detection of K-ras mutations in stool.

Clinical chemistry - 1 Mar 2002

Prix Lothar, Uciechowski Peter, Böckmann Beatrix, Giesing Michael, Schuetz Andreas J

Abstract excerpt

BACKGROUND: Tumor cells that shed into stool are attractive targets for molecular screening and early detection of colon or pancreatic malignancies. We developed a diagnostic test to screen for 10 of the most common mutations of codons 12 and 13 of the K-ras gene by hybridization to a new biochip array. METHODS: DNA was isolated from 26 stool samples by column-based extraction from 9 cell lines. Peptide nucleic...

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PMID: 11861435

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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