Article
Amplification refractory mutation system linear extension: a novel, gel-free, enzyme-linked immunoassay method for DNA genotyping.
Diagnostic molecular pathology : the American journal of surgical pathology, part B - 1 Oct 1998
Haque K, Hehir J, Fox J C, Newton C R, Little S
Abstract excerpt
A single synthesis cycle of the amplification refractory mutation system (ARMS) was applied to the analysis of K-ras alleles amplified by polymerase chain reaction and immobilized in streptavidin-coated microtiter plates. The ARMS cycle provided the specificity and molecular switch characteristics of a conventional ARMS assay. This allowed linear extension from an allele-specific primer and the incorporation of...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
