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Article

The proliferation of normal human fibroblasts is dependent upon negative regulation of p53 function by mdm2

25 Jun 1998

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Identifiers

PMID: 9681831
DOI: 10.1038/sj.onc.1201880

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

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The proliferation of normal human fibroblasts is dependent upon negative regulation of p53 function by mdm2PMID 9681831Read ↗

Tumour suppressor p53 inhibits human fibroblast growth factor 2 expression by a post-transcriptional mechanismSemantic proximity Read ↗

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Keeping p53 in check: essential and synergistic functions of Mdm2 and Mdm4.Semantic proximity Read ↗

Regulation of Transcription Functions of the p53 Tumor Suppressor by the mdm-2 OncogeneSemantic proximity Read ↗

The human oncoprotein MDM2 arrests the cell cycle: elimination of its cell‐cycle‐inhibitory function induces tumorigenesisSemantic proximity Read ↗

Myc and E2F1 induce p53 through p14ARF-independent mechanisms in human fibroblastsSemantic proximity Read ↗

The tumorigenic potential and cell growth characteristics of p53-deficient cells are equivalent in the presence or absence of Mdm2.Semantic proximity Read ↗

Mdm2 Affects Genome Stability Independent of p53Semantic proximity Read ↗

Dual action of the inhibitors of cyclin-dependent kinases: targeting of the cell-cycle progression and activation of wild-type p53 protein.Semantic proximity Read ↗

mdm2 deletion does not alter growth characteristics of p53-deficient embryo fibroblasts.Semantic proximity Read ↗

Regulation of p53 stability by Mdm2.Semantic proximity Read ↗

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