Article
Unexpected behavior of a gene trap vector comprising a fusion between the Sh ble and the lacZ genes.
Molecular reproduction and development - 1 Nov 1996
Camus A, Kress C, Babinet C, Barra J
Abstract excerpt
A new gene trap vector has been designed, comprised of a fusion between the Sh ble gene, which confers resistance to the antibiotic phleomycin, and the lacZ gene (phleal fusion gene). A synthetic splice acceptor, made of the yeast branchpoint followed by a pyrimidin-rich sequence of 27 nucleotides, is included at the 5' extremity. The linearized gene trap vector was introduced into mouse embryonic stem cells (ES...
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