Article
Reversibly Immortalized Mouse Articular Chondrocytes Acquire Long-Term Proliferative Capability While Retaining Chondrogenic Phenotype.
Cell transplantation - 1 Jan 2015
Lamplot Joseph D, Liu Bo, Yin Liangjun, Zhang Wenwen, Wang Zhongliang, Luther Gaurav, Wagner Eric, Li Ruidong, Nan Guoxin, Shui Wei, Yan Zhengjian, Rames Richard, Deng Fang, Zhang Hongmei, Liao Zhan, Liu Wei, Zhang Junhui, Zhang Zhonglin, Zhang Qian, Ye Jixing, Deng Youlin, Qiao Min, Haydon Rex C, Luu Hue H, Angeles Jovito, Shi Lewis L, He Tong-Chuan, Ho Sherwin H
Abstract excerpt
Cartilage tissue engineering holds great promise for treating cartilaginous pathologies including degenerative disorders and traumatic injuries. Effective cartilage regeneration requires an optimal combination of biomaterial scaffolds, chondrogenic seed cells, and biofactors. Obtaining sufficient chondrocytes remains a major challenge due to the limited proliferative capability of primary chondrocytes. Here we...
Topics
- Animals
- Antigens, Viral, Tumor
- Biomarkers
- Cartilage, Articular
- Cell Aggregation
- Cell Line, Transformed
- Cell Proliferation
- Cell Separation