Article
Immortalization and characterization of mouse temporomandibular joint disc cell clones with capacity for multi-lineage differentiation.
Osteoarthritis and cartilage - 1 Sept 2015
Park Y, Hosomichi J, Ge C, Xu J, Franceschi R, Kapila S
Abstract excerpt
OBJECTIVE: Despite the importance of temporomandibular joint (TMJ) disc in normal function and disease, studying the responses of its cells has been complicated by the lack of adequate characterization of the cell subtypes. The purpose of our investigation was to immortalize, clone, characterize and determine the multi-lineage potential of mouse TMJ disc cells. DESIGN: Cells from 12-week-old female mice were...
Topics
- Animals
- Blotting, Western
- Cartilage Oligomeric Matrix Protein
- Cell Differentiation
- Cell Line
- Clone Cells
- Female
- Fibrocartilage
- Humans
- Immunohistochemistry
- Menisci, Tibial
- Mice
- Phenotype
- Polymerase Chain Reaction