Article
Simple determination of human immunodeficiency virus type 1 syncytium-inducing V3 genotype by PCR.
Journal of clinical microbiology - 1 Apr 1995
Fouchier R A, Brouwer M, Broersen S M, Schuitemaker H
Abstract excerpt
Human immunodeficiency virus type 1 (HIV-1) phenotype variability plays an important role in the pathogenesis of AIDS. The presence of syncytium-inducing (SI) HIV-1 isolates in infected individuals is associated with a rapid decline of CD4+ T cells, rapid disease progression, and reduced survival time after AIDS diagnosis. The strong association between the SI capacity of HIV-1 and the presence of positively...
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