Article
Analysis of chromosome 17p13 (p53 locus) alterations in gastric carcinoma cells by dual-color fluorescence in situ hybridization.
The American journal of pathology - 1 Nov 1996
Kobayashi M, Kawashima A, Mai M, Ooi A
Abstract excerpt
Chromosome 17 and p53 gene locus alterations were determined on 67 gastric carcinomas by dual-color fluorescence in situ hybridization, using probes for centromere 17 and the 17p13.1 (p53 locus). The results were compared with loss of heterozygosity (LOH) at 17p13.3, direct sequencing of exons 5...
Topics
- Carcinoma
- Chromosome Aberrations
- Chromosome Disorders
- Chromosomes, Human, Pair 17
- Genes, p53
- Humans
- Immunohistochemistry
- In Situ Hybridization, Fluorescence
- Mutation
- Polymorphism, Restriction Fragment Length
- Stomach Neoplasms
