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Article

Use of dominant negative mutants of the hepadnaviral core protein as antiviral agents.

Hepatology (Baltimore, Md.) - 1 Nov 1996

Scaglioni P, Melegari M, Takahashi M, Chowdhury J R, Wands J

Abstract excerpt

Chronic hepatitis B virus (HBV) infection is a major cause of acute and chronic liver diseases. We have recently described HBV and woodchuck hepatitis virus (WHV) dominant negative (DN) core mutants that were capable of inhibiting wild-type viral replication by 95%. These mutants may represent a...

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PMID: 8903368
DOI: 10.1002/hep.510240506

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-8903368-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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Use of dominant negative mutants of the hepadnaviral core protein as antiviral agents.PMID 8903368Read ↗

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