Inhibition of duck hepatitis B virus replication by intrahepatic expression of an antiviral resistance gene.

Abstract excerpt

Resistance genes coding for inhibitors of hepadnaviral replication, such as ribozymes, antisense RNA, and dominant negative mutants have been shown to be effective in transfected hepatoma cells. In vivo studies, however, are not available to date. Here we expanded the use of the duck hepatitis B...

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