Article
Association study of a null mutation in the dopamine D4 receptor gene in Italian patients with obsessive-compulsive disorder, bipolar mood disorder and schizophrenia.
Psychiatric genetics - 1 Jan 1996
Di Bella D, Catalano M, Cichon S, Nöthen M M
Abstract excerpt
Although serotonergic dysregulation is a leading pathogenetic hypothesis for obsessive-compulsive disorder (OCD), some evidence also suggests a possible dysregulation of the dopaminergic system in this disorder. Therefore, individual differences in deoxyribonucleic acid (DNA) coding for dopamine...
Topics
- Bipolar Disorder
- Exons
- Genetic Variation
- Humans
- Italy
- Obsessive-Compulsive Disorder
- Polymerase Chain Reaction
- Polymorphism, Genetic
- Receptors, Dopamine D2
- Receptors, Dopamine D4
- Reference Values
- Schizophrenia
- Sequence Deletion