Article
Association analysis between a VNTR intron 8 polymorphism of the dopamine transporter gene (SLC6A3) and obsessive- compulsive disorder in a Brazilian sample.
Arquivos de neuro-psiquiatria - 1 Dec 2007
Miguita Karen, Cordeiro Quirino, Siqueira-Roberto Jacqueline, Shavitt Roseli Gedanke, Castillo José Carlos Ramos, Castillo Ana Regina, Miguel Euripedes Constantino, Vallada Homero
Abstract excerpt
Family, twin and segregation analysis have provided evidences that genetic factors are implicated in the susceptibility for obsessive-compulsive disorder (OCD). Several lines of research suggest that the dopaminergic system may be involved in the pathophysiology of OCD. Thus, the aim of the present study was to investigate a possible association between a polymorphism located in intron 8 of the dopamine...
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