Article
Investigation of dopamine system genes in obsessive-compulsive disorder.
Psychiatric genetics - 1 Jan 1998
Billett E A, Richter M A, Sam F, Swinson R P, Dai X Y, King N, Badri F, Sasaki T, Buchanan J A, Kennedy J L
Abstract excerpt
Evidence from anatomical, pharmacological, and animal studies on the involvement of the dopamine system in obsessive-compulsive disorder (OCD) is mounting. This, along with evidence for a genetic diathesis provided by family and twin studies, prompted us to conduct genetic association studies of dopamine system genes in OCD. We genotyped OCD patients (n > 100) and matched controls for four loci: (1) a...
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