Article
Investigation of dopamine system genes in obsessive-compulsive disorder.
Psychiatric genetics - 1 Jan 1998
Billett E A, Richter M A, Sam F, Swinson R P, Dai X Y, King N, Badri F, Sasaki T, Buchanan J A, Kennedy J L
Abstract excerpt
Evidence from anatomical, pharmacological, and animal studies on the involvement of the dopamine system in obsessive-compulsive disorder (OCD) is mounting. This, along with evidence for a genetic diathesis provided by family and twin studies, prompted us to conduct genetic association studies of...
Topics
- Age of Onset
- Alleles
- Carrier Proteins
- Dopamine
- Dopamine Plasma Membrane Transport Proteins
- Female
- Genetic Predisposition to Disease
- Genotype
- Humans
- Male
- Membrane Glycoproteins
- Membrane Transport Proteins
- Nerve Tissue Proteins
- Obsessive-Compulsive Disorder
- Polymorphism, Restriction Fragment Length