Article
Identification of two novel polymorphisms and a rare deletion variant in the human dopamine D4 receptor gene.
Psychiatric genetics - 1 Jan 1995
Cichon S, Nöthen M M, Catalano M, Di Bella D, Maier W, Lichtermann D, Minges J, Albus M, Borrmann M, Franzek E
Abstract excerpt
We report two novel polymorphisms and a rare deletion variant in the human dopaine D4 receptor gene. The two polymorphisms are characterized by single base pair substitutions, namely a G-->C transversion changing codon 11 from GGG (encoding Gly) to CGG (encoding Arg) and a C-->T transition in pos...
Topics
- Adult
- Age of Onset
- Amino Acid Sequence
- Base Sequence
- Bipolar Disorder
- Codon
- DNA
- DNA Primers
- Exons
- Gene Frequency
- Genetic Variation
- Humans
- Leukocytes
- Middle Aged
- Molecular Sequence Data
- Obsessive-Compulsive Disorder
- Panic Disorder
- Point Mutation