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Article

A molecular investigation suggests no relationship between obsessive-compulsive disorder and the dopamine D2 receptor.

Neuropsychobiology - 1 Jan 1994

Novelli E, Nobile M, Diaferia G, Sciuto G, Catalano M

Abstract excerpt

Some studies suggest a relationship between obsessive-compulsive disorder (OCD) and Gilles de la Tourette's syndrome. The pathophysiology of the latter may involve the dopamine system. We screened three important exons of the dopamine D2 receptor (DRD2) gene for mutations in a group of OCD patien...

Topics

Adolescent
Adult
Aged
Base Sequence
DNA
Exons
Female
Genotype
Humans
Male
Middle Aged
Molecular Sequence Data
Obsessive-Compulsive Disorder

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Receptors, Dopamine D2

Tic Disorders

Source

Identifiers

PMID: 8170527
DOI: 10.1159/000119065

Genes

DRD2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-8170527-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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A molecular investigation suggests no relationship between obsessive-compulsive disorder and the dopamine D2 receptor.PMID 8170527Read ↗

Association study between the dopamine receptor D(4) gene and obsessive-compulsive disorder.Semantic proximity Read ↗

DRD2, DRD3 and 5HT2A receptor genes polymorphisms in obsessive-compulsive disorder.Semantic proximity Read ↗

Association between the dopamine receptor D4 (DRD4) gene and obsessive-compulsive disorder.Semantic proximity Read ↗

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Association study of a null mutation in the dopamine D4 receptor gene in Italian patients with obsessive-compulsive disorder, bipolar mood disorder and schizophrenia.Semantic proximity Read ↗

Lack of association between obsessive-compulsive disorder and the dopamine D3 receptor gene: some preliminary considerations.Semantic proximity Read ↗

Association analysis between a VNTR intron 8 polymorphism of the dopamine transporter gene (SLC6A3) and obsessive- compulsive disorder in a Brazilian sample.Semantic proximity Read ↗

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Increased prevalence of the seven-repeat variant of the dopamine D4 receptor gene in patients with obsessive-compulsive disorder with tics.Semantic proximity Read ↗

T102C and -1438 G/A polymorphisms of the 5-HT2A receptor gene in Turkish patients with obsessive-compulsive disorder.Semantic proximity Read ↗

Use of polymerase chain reaction nad denaturing gradient gel electrophoresis to identify polymorphisms in three exons of dopamine D2 receptor gene in schizophrenic and delusional patients.Semantic proximity Read ↗

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