Article
Multicopy suppressor analysis of thermosensitive YIP1 alleles implicates GOT1 in transport from the ER.
Journal of cell science - 15 May 2009
Lorente-Rodríguez Andrés, Heidtman Matthew, Barlowe Charles
Abstract excerpt
Yip1p belongs to a conserved family of membrane-spanning proteins that are involved in intracellular trafficking. Studies have shown that Yip1p forms a heteromeric integral membrane complex, is required for biogenesis of ER-derived COPII vesicles, and can interact with Rab GTPases. However, the role of the Yip1 complex in vesicle budding is not well understood. To gain further insight, we isolated multicopy...
Topics
- Alleles
- COP-Coated Vesicles
- Endoplasmic Reticulum
- Fungal Proteins
- Genes, Suppressor
- Golgi Apparatus
- Intracellular Membranes
- Molecular Weight
- Multiprotein Complexes
- Mutation
- Protein Transport
- Recombinant Fusion Proteins
- Saccharomycetales
- Temperature
- Vesicular Transport Proteins