The dilute-lethal (dl) gene attacks a Ca2+ store in the dendritic spine of Purkinje cells in mice.

doi:10.1016/0304-3940(96)12967-0

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Article

The dilute-lethal (dl) gene attacks a Ca2+ store in the dendritic spine of Purkinje cells in mice.

Neuroscience letters - 13 Sept 1996

Takagishi Y, Oda S, Hayasaka S, Dekker-Ohno K, Shikata T, Inouye M, Yamamura H

Abstract excerpt

The absence of smooth endoplasmic reticulum (SER) in the dendritic spine of Purkinje cells was found in dilute-lethal (dl) mouse cerebella as detected by immunohistochemistry using anti-inositol 1,4,5-triphosphate receptor antibody and electron microscopy. Since SER in the spine has been suggeste...

Topics

Animals
Calcium
Cerebellum
Dendrites
Genes, Lethal
Mice
Mice, Mutant Strains
Microscopy, Electron
Mutation
Purkinje Cells

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