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Article

The use of transgenic mouse models to reveal the functions of Ca2+ buffer proteins in excitable cells.

Biochimica et biophysica acta - 1 Aug 2012

Schwaller Beat

Abstract excerpt

BACKGROUND: Cytosolic Ca2+ buffers are members of the large family of Ca2+-binding proteins and are essential components of the Ca2+ signaling toolkit implicated in the precise regulation of intracellular Ca2+ signals. Their physiological role in excitable cells has been investigated in vivo by analyzing the phenotype of mice either lacking one of the Ca2+ buffers or mice with ectopic expression. SCOPE OF REVIEW:...

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PMID: 22138448
DOI: 10.1016/j.bbagen.2011.11.008

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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