Article
The Dictyostelium dual-specificity kinase splA is essential for spore differentiation.
Development (Cambridge, England) - 1 Oct 1996
Nuckolls G H, Osherov N, Loomis W F, Spudich J A
Abstract excerpt
We have studied the structure and function of the Dictyostelium kinase splA. A truncated form of the splA protein exhibited primarily tyrosine kinase activity in vitro; however, it also autophosphorylated on serine and threonine residues. The kinase domain of splA exhibits approximately 38% identity to the CTR1 kinase of Arabidopsis, which is a member of the Raf family. Outside its kinase domain, splA shares...
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