Article
The STRIPAK signaling complex regulates dephosphorylation of GUL1, an RNA-binding protein that shuttles on endosomes.
PLoS genetics - 1 Sept 2020
Stein Valentina, Blank-Landeshammer Bernhard, Müntjes Kira, Märker Ramona, Teichert Ines, Feldbrügge Michael, Sickmann Albert, Kück Ulrich
Abstract excerpt
The striatin-interacting phosphatase and kinase (STRIPAK) multi-subunit signaling complex is highly conserved within eukaryotes. In fungi, STRIPAK controls multicellular development, morphogenesis, pathogenicity, and cell-cell recognition, while in humans, certain diseases are related to this signaling complex. To date, phosphorylation and dephosphorylation targets of STRIPAK are still widely unknown in microbial...
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