Article
A Serum Response Factor homolog is required for spore differentiation in Dictyostelium.
Development (Cambridge, England) - 1 Oct 1998
Escalante R, Sastre L
Abstract excerpt
A homolog of the Serum Response Factor (SRF) has been isolated from Dictyostelium discoideum and its function studied by analyzing the consequences of its gene disruption. The MADS-box region of Dictyostelium SRF (DdSRF) is highly conserved with those of the human, Drosophila and yeast homologs. srfA is a developmentally regulated gene expressed in prespore and spore cells. This gene plays an essential role in...
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