Article
A Serum Response Factor homolog is required for spore differentiation in Dictyostelium.
Development (Cambridge, England) - 1 Oct 1998
Escalante R, Sastre L
Abstract excerpt
A homolog of the Serum Response Factor (SRF) has been isolated from Dictyostelium discoideum and its function studied by analyzing the consequences of its gene disruption. The MADS-box region of Dictyostelium SRF (DdSRF) is highly conserved with those of the human, Drosophila and yeast homologs....
Topics
- 8-Bromo Cyclic Adenosine Monophosphate
- Amino Acid Sequence
- Animals
- Cell Differentiation
- Cyclic AMP-Dependent Protein Kinases
- DNA-Binding Proteins
- Dictyostelium
- Enzyme Activation
- Gene Expression Regulation, Developmental
- Genes, Protozoan
- Humans
- Molecular Sequence Data
- Mutation
- Nuclear Proteins
- Protozoan Proteins
- RNA, Messenger
- RNA, Protozoan
- Sequence Homology, Amino Acid