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Article

Biochemical and genetic characterization of multiple splice variants of the Flt3 ligand

1 Nov 1996

Abstract excerpt

We have performed a comprehensive analysis of cell lines and tissues to compare and contrast the expression patterns of Flt3 ligand (FL), c-Kit ligand (KL), and macrophage colony-stimulating factor as well as their receptors, Flt3, c-Kit, and c-Fms. The message for FL is unusually ubiquitous, whereas that of its receptor is quite restricted, apparently limiting the function of the ligand to fetal development and...

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PMID: 8896402
DOI: 10.1182/blood.v88.9.3371.bloodjournal8893371

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