Article
Expression and immunochemical analysis of rat and human fibroblast growth factor receptor (flg) isoforms.
The Journal of biological chemistry - 5 Sept 1992
Xu J, Nakahara M, Crabb J W, Shi E, Matuo Y, Fraser M, Kan M, Hou J, McKeehan W L
Abstract excerpt
Potentially 96 splice variants among four genes that code for the human heparin-binding fibroblast growth factor receptor family complicate study of structure, metabolism, and function of single isoforms in mammalian cells. As an alternative, we expressed structural subdomains and isoforms of the flg receptor gene in bacteria and baculoviral-infected insect cells. We developed and characterized a panel of 16...
Topics
- Amino Acid Sequence
- Animals
- Antibodies
- Baculoviridae
- Base Sequence
- Blotting, Western
- Cell Line
- Cell Membrane
- Fibroblast Growth Factors
- Filaggrin Proteins
- Genetic Variation
