Stable inheritance of an HLA-"blank" phenotype associated with a structural mutation in the HLA-A*0301 gene.

doi:10.1111/j.1399-0039.1996.tb02627.x

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Article

Stable inheritance of an HLA-"blank" phenotype associated with a structural mutation in the HLA-A*0301 gene.

Tissue antigens - 1 Sept 1996

Lienert K, Russ G, Lester S, Bennett G, Gao X, McCluskey J

Abstract excerpt

A serological family study identified an HLA-A "blank" segregating through three generations of apparently healthy individuals. The HLA-A*0301 allele was assigned by DNA genotyping in each of the three individuals. Complete absence of cellular expression of the HLA-A3 antigen was associated with...

Topics

Base Sequence
Flow Cytometry
HLA-A3 Antigen
Humans
Molecular Sequence Data
Mutation
Pedigree
Phenotype

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