Article
A novel HLA-B null allele (B*4022N) generated by a nonsense codon in the alpha1 domain.
Tissue antigens - 1 Apr 2000
Tamouza R, Sadki K, Schaeffer V, Carbonnelle E, Tatari Z, Chabod J, Toubert A, Raffoux C, Sayada C, Charron D
Abstract excerpt
We describe in this work a novel HLA-B null allele designated B*4022N. This new variant was found in a Caucasian individual who was serologically typed for one HLA-B allele as a B-blank, Bw-blank. Retrospective DNA typing by polymerase chain reaction using sequence-specific primers (PCR-SSP) has established the correspondence of this blank allele with the classical HLA-B*4001 allele. Nucleotide sequence analysis...
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