Article
Natural inactivation of a common HLA allele (A*2402) has occurred on at least three separate occasions.
Journal of immunology (Baltimore, Md. : 1950) - 1 Jun 1997
Magor K E, Taylor E J, Shen S Y, Martinez-Naves E, Valiante N M, Wells R S, Gumperz J E, Adams E J, Little A M, Williams F, Middleton D, Gao X, McCluskey J, Parham P, Lienert-Weidenbach K
Abstract excerpt
HLA-A*2402 is common and widely distributed in human populations. Several individuals were identified who type genotypically for A*2402, but are serologically null for the HLA-A24 Ag. Sequencing and transfection of genomic DNA fragments containing null and wild-type A*2402 alleles, and the related A*2301 allele, revealed three different null alleles (A*2409N, A*2411N, and A*2402(low)), each of which differs from...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
