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Article

Genotypic analysis of infant macaques infected transplacentally and orally.

Journal of medical primatology - 1 Jun 1996

Martin Amedee A, Lacour N, Martin L N, Clements J E, Bohm R B, Davison B, Harrison R, Murphey-Corb M

Abstract excerpt

The SIV-infected macaque provides an excellent model to study factors involved in maternal-fetal transmission of HIV. In our prenatal transmission studies, female macaques were inoculated intravenously during midgestation with either SIV/DeltaB670 or a combination of SIV/ DeltaB670 and the macrophage-tropic molecular clone SIV/17E-Fr. The females harbored a genetically diverse virus population at parturition,...

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Source

Identifiers

PMID: 8892044
DOI: 10.1111/j.1600-0684.1996.tb00020.x

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