Article
Genotypic selection of simian immunodeficiency virus in macaque infants infected transplacentally.
Journal of virology - 1 Dec 1995
Amedee A M, Lacour N, Gierman J L, Martin L N, Clements J E, Bohm R, Harrison R M, Murphey-Corb M
Abstract excerpt
To understand viral and host factors that contribute to transplacental transmission of human immunodeficiency virus, we developed an animal model using pregnant female macaques infected with simian immunodeficiency virus (SIV). Pregnant females were inoculated intravenously during midgestation with either a well-characterized primary isolate of SIV (SIV/DeltaB670) or a combination of SIV/DeltaB670 and the...
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