Article
SIV/DeltaB670 transmission across oral, colonic, and vaginal mucosae in the macaque.
Journal of medical primatology - 1 Jan 2000
Trichel A M, Roberts E D, Wilson L A, Martin L N, Ruprecht R M, Murphey-Corb M
Abstract excerpt
The primary mode of human immunodeficiency virus (HIV) transmission worldwide is by exposure to the virus at vaginal, rectal, and oral mucosal surfaces. To understand HIV/simian immunodeficiency virus (SIV) transmission events at mucosal portals of entry, we used the SIV-macaque model to determine if mucosal surfaces function as barriers and select for particular viral genotypes. Rhesus macaques were inoculated...
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