Article
The vertical transmission of human immunodeficiency virus type 1: molecular and biological properties of the virus.
Critical reviews in clinical laboratory sciences - 1 Jan 2005
Ahmad Nafees
Abstract excerpt
The vertical (mother-to-infant) transmission of human immunodeficiency virus type 1 (HIV-1 ) occurs at an estimated rate of more than 30% and is the major cause of AIDS in children. Numerous maternal parameters, including advanced dinical stages, low CD4+ lymphocte counts, high viral load, immune response, and disease progression have been implicated in an increased risk of vertical transmission. While the use of...
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