Article
Molecular genetic analysis of chromosome arm 17p and chromosome arm 22q DNA sequences in sporadic pediatric ependymomas.
Genes, chromosomes & cancer - 1 Sept 1996
von Haken M S, White E C, Daneshvar-Shyesther L, Sih S, Choi E, Kalra R, Cogen P H
Abstract excerpt
Ependymomas are glial tumors of the brain and spinal cord occurring both sporadically and in a familial syndrome, neurofibromatosis type 2 (NF2). Previous analyses performed on specimens obtained predominantly from adult patients have shown loss of DNA sequences from chromosome arm 22q, which is...
Topics
- Adolescent
- Blotting, Southern
- Brain Neoplasms
- Child
- Child, Preschool
- Chromosome Deletion
- Chromosomes, Human, Pair 17
- Chromosomes, Human, Pair 22
- Ependymoma
- Female
- Genes, Neurofibromatosis 2
- Genes, p53
- Humans
- Infant
- Male
- Microsatellite Repeats
- Mutation
- Polymorphism, Restriction Fragment Length