Article
Molecular genetic analysis of chromosome arm 17p and chromosome arm 22q DNA sequences in sporadic pediatric ependymomas.
Genes, chromosomes & cancer - 1 Sept 1996
von Haken M S, White E C, Daneshvar-Shyesther L, Sih S, Choi E, Kalra R, Cogen P H
Abstract excerpt
Ependymomas are glial tumors of the brain and spinal cord occurring both sporadically and in a familial syndrome, neurofibromatosis type 2 (NF2). Previous analyses performed on specimens obtained predominantly from adult patients have shown loss of DNA sequences from chromosome arm 22q, which is the location of the NF2 gene. Previously, we documented the consistent loss of chromosome arm 17p DNA in...
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