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Article

Generation of hepatocytes from oval cell precursors in culture.

Cancer research - 1 Dec 1998

Lázaro C A, Rhim J A, Yamada Y, Fausto N

Abstract excerpt

Although there is experimental evidence supporting the involvement of hepatic stem cells in the pathogenesis of liver cancers, the detection and isolation of these cells remains elusive. A logical approach to detecting these cells would take advantage of their ability to differentiate (or to give rise to cells that differentiate) into hepatocytes. This approach requires an assay system that is conducive to...

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PMID: 9850088

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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Generation of hepatocytes from oval cell precursors in culture.PMID 9850088Read ↗

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Mature hepatocytes exhibit unexpected plasticity by direct dedifferentiation into liver progenitor cells in culture.Semantic proximity Read ↗

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Putative liver progenitor cells: conditions for long-term survival in culture.Semantic proximity Read ↗

Phenotype and differentiation patterns of the oval cell lines OC/CDE 6 and OC/CDE 22 derived from the livers of carcinogen-treated rats.Semantic proximity Read ↗

Oval cell lines OC/CDE 6 and OC/CDE 22 give rise to cholangio-cellular and undifferentiated carcinomas after transformation.Semantic proximity Read ↗

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Pluripotential liver stem cells: facultative stem cells located in the biliary treeSemantic proximity Read ↗

Primary isolated hepatic oval cells maintain progenitor cell phenotypes after two-year prolonged cultivation.Semantic proximity Read ↗

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