Article
Remarkable heterogeneity displayed by oval cells in rat and mouse models of stem cell-mediated liver regeneration.
Hepatology (Baltimore, Md.) - 1 Jun 2007
Jelnes Peter, Santoni-Rugiu Eric, Rasmussen Morten, Friis Susanne Lunøe, Nielsen Jens Høiriis, Tygstrup Niels, Bisgaard Hanne Cathrine
Abstract excerpt
UNLABELLED: The experimental protocols used in the investigation of stem cell-mediated liver regeneration in rodents are characterized by activation of the hepatic stem cell compartment in the canals of Hering followed by transit amplification of oval cells and their subsequent differentiation along hepatic lineages. Although the protocols are numerous and often used interchangeably across species, a thorough...
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