Article
Hypertriglyceridemia and the apolipoprotein CIII gene locus: lack of association with the variant insulin response element in Italian school children.
Human genetics - 1 Nov 1996
Shoulders C C, Grantham T T, North J D, Gaspardone A, Tomai F, de Fazio A, Versaci F, Gioffre P A, Cox N J
Abstract excerpt
Hypertriglyceridemia is a common metabolic disorder with a major inherited component. In some individuals the condition is suspected to occur as a result of overproduction of apolipoprotein (apo)CIII, a major constituent of triglyceride-rich lipoproteins. Population studies have established an association with the apoCIII gene but the identify of the causal mutation remains unknown. In the present study we have...
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