Article
Genetic heterogeneity in the apolipoprotein C-III promoter and effects of insulin.
Journal of lipid research - 1 Sept 2001
Dallinga-Thie G M, Groenendijk M, Blom R N, De Bruin T W, De Kant E
Abstract excerpt
In the present study, we have investigated the in vivo and in vitro role of two newly identified variants (G(-)944A and A(-)1180C) located in the upstream promoter region of the apolipoprotein C-III (apoC-III) gene. These variants were studied in 30 probands diagnosed with FCHL, their relatives, and spouses. The allele frequencies of both variants were not different between the groups. No significant associations...
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