Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Interaction between insulin (VNTR) and hepatic lipase (LIPC-514C>T) variants on the response to an oral glucose tolerance test in the EARSII group of young healthy men.

Biochimica et biophysica acta - 10 Jun 2005

Waterworth Dawn M, Jansen Hans, Nicaud Viviane, Humphries Steve E, Talmud Philippa J

Abstract excerpt

Insulin resistance is polygenic in origin, and can be observed at an early age. We have shown that variations in APOC3-482T>C and hepatic lipase (LIPC)-514C>T), individually (APOC3 alone) and interactively, modulate insulin and glucose levels after an OGTT in young healthy men participating in th...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Apolipoprotein C-III
Share to Apolipoproteins C
Share to Exercise

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Glucose Tolerance Test

Share to Insulin

Share to Insulin Resistance

Share to Lipase

Share to Minisatellite Repeats

Source

Identifiers

PMID: 15949705
DOI: 10.1016/j.bbadis.2004.09.007

Genes

INS
APOC3
LIPC

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-15949705-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Interaction between insulin (VNTR) and hepatic lipase (LIPC-514C>T) variants on the response to an oral glucose tolerance test in the EARSII group of young healthy men.PMID 15949705Read ↗

Interaction of the common apolipoprotein C-III (APOC3 -482C > T) and hepatic lipase (LIPC -514C > T) promoter variants affects glucose tolerance in young adults. European Atherosclerosis Research Study II (EARS-II).Semantic proximity Read ↗

The -514 C/T polymorphism in the hepatic lipase gene promoter is associated with insulin sensitivity in a healthy young population.Semantic proximity Read ↗

Variants in the APOC3 promoter insulin responsive element modulate insulin secretion and lipids in middle-aged men.Semantic proximity Read ↗

ApoCIII gene variants modulate postprandial response to both glucose and fat tolerance tests.Semantic proximity Read ↗

IRS1 gene variants, dysglycaemic metabolic changes and type-2 diabetes risk.Semantic proximity Read ↗

Gene variants, insulin resistance, and dyslipidaemia.Semantic proximity Read ↗

Effects of variations in the APOA1/C3/A4/A5 gene cluster on different parameters of postprandial lipid metabolism in healthy young men.Semantic proximity Read ↗

Variable effects of the APOC3-482C > T variant on insulin, glucose and triglyceride concentrations in different ethnic groups.Semantic proximity Read ↗

The combination of ApoCIII, hepatic lipase and hormono sensitive lipase gene polymorphisms suggests an association with susceptibility to gestational hypertension.Semantic proximity Read ↗

The SstI polymorphism of the apo C-III gene is associated with insulin sensitivity in young men.Semantic proximity Read ↗

Genetic variation within IL18 is associated with insulin levels, insulin resistance and postprandial measures.Semantic proximity Read ↗

Effect of genetic variation on the postprandial response. Results from the European Atherosclerosis Research Study II.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.