Article
Variation at the apo AI/CIII/AIV gene complex is associated with elevated plasma levels of apo CIII.
Atherosclerosis - 1 Apr 1991
Shoulders C C, Harry P J, Lagrost L, White S E, Shah N F, North J D, Gilligan M, Gambert P, Ball M J
Abstract excerpt
A number of studies have reported that a variant allele (S2) of the apo AI/CIII/AIV complex is associated with high plasma lipid levels in some populations and furthermore that the frequency of this allele is 2-5-fold higher in patient groups with premature coronary heart disease compared to control groups. This study shows in the healthy "English" population that the S2 allele is associated with elevated plasma...
Topics
- Adult
- Alleles
- Apolipoprotein A-I
- Apolipoprotein C-III
- Apolipoproteins A
- Apolipoproteins C
- Cholesterol
- Cholesterol, HDL
- Cholesterol, LDL
- Cholesterol, VLDL
- Female