Article
Structural mutations in the constant region of the T-cell antigen receptor (TCR)beta chain and their effect on TCR alpha and beta chain interaction.
Immunology - 1 Aug 1996
Li Z G, Wu W P, Manolios N
Abstract excerpt
The region responsible for T-cell receptor (TCR)alpha and beta chain assembly has previously been shown to reside in their extracellular domains. In an attempt to delineate further the structural requirements for TCR alpha and beta chain assembly, chimeric TCR beta chains with increasing length o...
Topics
- Base Sequence
- Disulfides
- Electrophoresis, Gel, Two-Dimensional
- Humans
- Immunoglobulin Constant Regions
- Molecular Sequence Data
- Mutation
- Receptors, Antigen, T-Cell, alpha-beta
- Structure-Activity Relationship
- T-Lymphocytes
