Article
Cloning and chromosomal mapping of the mouse DNA-dependent protein kinase gene.
Immunogenetics - 1 Jan 1996
Hamatani K, Matsuda Y, Araki R, Itoh M, Abe M
Abstract excerpt
Severe combined immune deficiency (scid) mice are assumed to have two types of abnormalities: one is high radiosensitivity and the other is abnormal recombination in immunoglobulin and T-cell receptor genes. The human chromosome 8 q1.1 region has an ability to complement the scid aberrations. Moreover, the localization of the subunit DNA-dependent protein kinase [DNA-PKcs] participating in DNA double-strand break...
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