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Article

Gene for the catalytic subunit of mouse DNA-dependent protein kinase maps to the scid locus.

Proceedings of the National Academy of Sciences of the United States of America - 7 Nov 1995

Miller R D, Hogg J, Ozaki J H, Gell D, Jackson S P, Riblet R

Abstract excerpt

The gene encoding the catalytic subunit of DNA-dependent protein kinase (DNA-PKcs) has been proposed recently as a candidate gene for the mouse severe combined immune deficiency (scid) locus. We have used a partial cDNA clone for human DNA-PKcs to map the mouse homologue using a large interspecific backcross panel. We found that the mouse gene for DNA-PKcs does not recombine with scid, consistent with the...

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Identifiers

PMID: 7479885
DOI: 10.1073/pnas.92.23.10792
PMCID: PMC40698

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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